Blood Test Could Predict Risk of Alzheimer’s, Dementia




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Scientists have developed a blood test that they say could lead to an early
diagnosis of Alzheimer’s disease and other forms of dementia in elderly people
long before the symptoms of the disease begin to manifest themselves.

A blood test
that can detect Alzheimer’s disease up to three years before the onset
of symptoms has been developed by scientists who believe that it could
lead to the early diagnosis of progressive dementia in elderly people.

A team led by Dr. Howard Federoff of the Georgetown University School of
Medicine has developed a test based on measuring the levels of ten fatty
chemicals — commonly called lipids — in the blood. As membranes of the brain
cells affected by Alzheimer’s begin to break down, the levels of the lipids
decrease.


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The Georgetown team analyzed blood samples from 525 volunteers, all of whom
were over the age of 70. Halfway through a five-year period, the team compared
blood samples from 53 patients who were already affected by either Alzheimer’s
disease or mild cognitive impairment (MCI) with samples from 53 patients who
were “cognitively normal.” They found that analyzing the lipid levels
could predict with 90 percent accuracy whether patients went on develop MCI or
Alzheimer’s within three years.

“We consider our results a major step toward the commercialization of a
pre-clinical disease biomarker test that could be useful for large-scale
screening to identify at-risk individuals.” Dr. Federoff wrote.


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Other researchers said that offering such a test would create an ethical
dilemma for doctors.
“Having such a test would be an interesting development, but it also
throws up ethical considerations,” Dr. Doug Brown, director of research
and development at Great Britain’s Alzheimer’s Society, told the Independent.
“If this does develop in the future, people must be given a choice about
whether they would want to know, and fully understand the implications.”
The full study will be published in the April issue of Nature
Medicine. 


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3 Comments on "Blood Test Could Predict Risk of Alzheimer’s, Dementia"

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chiboy okere
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卄丹卄丹 山◯山

osylove
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medically up to date….thats great…..keep updating us medically. 081382397

Mike Princess
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oh my word

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